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Hypoxia Enhances the Replication of Oncolytic Herpes Simplex Virus
Hypoxia contributes to the resistance of tumors to conventional therapies. We hypothesized that their replication in hypoxic environments like brain or oral mucosa would make oncolytic herpes simplex viruses (HSVs) such as G207 (which has undergone clinical trials) replicate to a greater extent in h...
שמור ב:
| Main Authors: | , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2008
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2823294/ https://ncbi.nlm.nih.gov/pubmed/18957963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.232 |
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