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Oncolytic herpes simplex virus immunovirotherapy in combination with immune checkpoint blockade to treat glioblastoma

Oncolytic viruses, such as oncolytic herpes simplex virus (oHSV), are a new class of cancer therapeutic, which selectively replicate and kill cancer cells, while inducing an inflammatory microenvironment, immunovirotherapy. Recently, an oHSV (talimogene laherparepvec) has been approved for the treat...

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Detalhes bibliográficos
Publicado no:Immunotherapy
Main Authors: Saha, Dipongkor, Martuza, Robert L, Rabkin, Samuel D
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6275562/
https://ncbi.nlm.nih.gov/pubmed/30008259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt-2018-0009
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