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Oncolytic herpes simplex virus interactions with the host immune system

Oncolytic viruses (OVs), like oncolytic herpes simplex virus (oHSV), are genetically engineered to selectively replicate in and kill cancer cells, while sparing normal cells. Initial OV infection, cell death, and subsequent OV propagation within the tumor microenvironment leads to a cascade of host...

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Detalhes bibliográficos
Publicado no:Curr Opin Virol
Main Authors: Saha, Dipongkor, Wakimoto, Hiroaki, Rabkin, Samuel D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138121/
https://ncbi.nlm.nih.gov/pubmed/27497296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2016.07.007
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