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Temozolomide antagonizes oncolytic immunovirotherapy in glioblastoma

BACKGROUND: Temozolomide (TMZ) chemotherapy is a current standard of care for glioblastoma (GBM), however it has only extended overall survival by a few months. Because it also modulates the immune system, both beneficially and negatively, understanding how TMZ interacts with immunotherapeutics is i...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Saha, Dipongkor, Rabkin, Samuel D, Martuza, Robert L
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7252967/
https://ncbi.nlm.nih.gov/pubmed/32457126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2019-000345
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