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Multifaceted oncolytic virus therapy for glioblastoma in an immunocompetent cancer stem cell model

Glioblastoma (World Health Organization grade IV) is an aggressive adult brain tumor that is inevitably fatal despite surgery, radiation, and chemotherapy. Treatment failures are attributed to combinations of cellular heterogeneity, including a subpopulation of often-resistant cancer stem cells, abe...

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Hlavní autoři: Cheema, Tooba A., Wakimoto, Hiroaki, Fecci, Peter E., Ning, Jianfang, Kuroda, Toshihiko, Jeyaretna, Deva S., Martuza, Robert L., Rabkin, Samuel D.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718117/
https://ncbi.nlm.nih.gov/pubmed/23754388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307935110
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