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DNA damage checkpoint triggers autophagy to regulate the initiation of anaphase
Budding yeast cells suffering a single unrepaired double-strand break (DSB) trigger the Mec1 (ATR)-dependent DNA damage response that causes them to arrest before anaphase for 12–15 h. Here we find that hyperactivation of the cytoplasm-to-vacuole (CVT) autophagy pathway causes the permanent G2/M arr...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3538254/ https://ncbi.nlm.nih.gov/pubmed/23169651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218065109 |
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