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Mad2 prolongs DNA damage checkpoint arrest caused by a double-strand break via a centromere-dependent mechanism
Eukaryotic cells employ a suite of replication and mitotic checkpoints to ensure the accurate transmission of their DNA. In budding yeast, both the DNA damage checkpoint and the spindle assembly checkpoint (SAC) block cells prior to anaphase [1-5]. The presence of a single unrepaired double-strand b...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2811853/ https://ncbi.nlm.nih.gov/pubmed/20096585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2009.12.033 |
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