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The yeast DNA damage checkpoint proteins control a cytoplasmic response to DNA damage

A single HO endonuclease-induced double-strand break (DSB) is sufficient to activate the DNA damage checkpoint and cause Saccharomyces cells to arrest at G(2)/M for 12–14 h, after which cells adapt to the presence of the DSB and resume cell cycle progression. The checkpoint signal leading to G(2)/M...

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Detalhes bibliográficos
Main Authors: Dotiwala, Farokh, Haase, Julian, Arbel-Eden, Ayelet, Bloom, Kerry, Haber, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1896138/
https://ncbi.nlm.nih.gov/pubmed/17586685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609636104
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