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Subcellular localization of yeast ribonucleotide reductase regulated by the DNA replication and damage checkpoint pathways

The fidelity of DNA replication and repair processes is critical for maintenance of genomic stability. Ribonucleotide reductase (RNR) catalyzes the rate-limiting step in dNTP production and thus plays an essential role in DNA synthesis. The level and activity of RNR are highly regulated by the cell...

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Detalhes bibliográficos
Main Authors: Yao, Ruojin, Zhang, Zhen, An, Xiuxiang, Bucci, Brigid, Perlstein, Deborah L., Stubbe, JoAnne, Huang, Mingxia
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164498/
https://ncbi.nlm.nih.gov/pubmed/12732713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1131932100
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