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Nuclear localization of the Saccharomyces cerevisiae ribonucleotide reductase small subunit requires a karyopherin and a WD40 repeat protein

Ribonucleotide reductase (RNR) catalyzes the reduction of ribonucleotides to the corresponding deoxyribonucleotides and is an essential enzyme for DNA replication and repair. Cells have evolved intricate mechanisms to regulate RNR activity to ensure high fidelity of DNA replication during normal cel...

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Bibliografiske detaljer
Main Authors: Zhang, Zhen, An, Xiuxiang, Yang, Kui, Perlstein, Deborah L., Hicks, Leslie, Kelleher, Neil, Stubbe, JoAnne, Huang, Mingxia
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360584/
https://ncbi.nlm.nih.gov/pubmed/16432237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510516103
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