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Structure of the yeast ribonucleotide reductase Y2Y4 heterodimer

The R2 subunits of class I ribonucleotide reductases (RNRs) house a diferric-tyrosyl radical (Y·) cofactor essential for DNA synthesis. In yeast, there are two R2 proteins, Y2 and Y4. Although both Y2 and Y4 are homologous to R2s from other organisms, Y4 lacks three conserved iron-binding residues,...

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Hlavní autoři: Voegtli, Walter C., Ge, Jie, Perlstein, Deborah L., Stubbe, JoAnne, Rosenzweig, Amy C.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC56917/
https://ncbi.nlm.nih.gov/pubmed/11526233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.181336398
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