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Structure of the yeast ribonucleotide reductase Y2Y4 heterodimer
The R2 subunits of class I ribonucleotide reductases (RNRs) house a diferric-tyrosyl radical (Y·) cofactor essential for DNA synthesis. In yeast, there are two R2 proteins, Y2 and Y4. Although both Y2 and Y4 are homologous to R2s from other organisms, Y4 lacks three conserved iron-binding residues,...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The National Academy of Sciences
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC56917/ https://ncbi.nlm.nih.gov/pubmed/11526233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.181336398 |
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