Functional link between mitochondria and Rnr3, the minor catalytic subunit of yeast ribonucleotide reductase

Ribonucleotide reductase (RNR) is an essential holoenzyme required for de novo synthesis of dNTPs. The Saccharomyces cerevisiae genome encodes for two catalytic subunits, Rnr1 and Rnr3. While Rnr1 is required for DNA replication and DNA damage repair, the function(s) of Rnr3 is unknown. Here, we sho...

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Главные авторы:	Isaac Corcoles-Saez, Jean-Luc Ferat, Michael Costanzo, Charles M. Boone, Rita S. Cha
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Shared Science Publishers OG 2019-05-01
Серии:	Microbial Cell
Предметы:	Rnr1 Rnr3 Mec1 carbon source respiration mitochondria dNTP
Online-ссылка:	http://microbialcell.com/researcharticles/2019a-corcoles-saez-microbial-cell/
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