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Functional link between mitochondria and Rnr3, the minor catalytic subunit of yeast ribonucleotide reductase

Ribonucleotide reductase (RNR) is an essential holoenzyme required for de novo synthesis of dNTPs. The Saccharomyces cerevisiae genome encodes for two catalytic subunits, Rnr1 and Rnr3. While Rnr1 is required for DNA replication and DNA damage repair, the function(s) of Rnr3 is unknown. Here, we sho...

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Principais autores: Isaac Corcoles-Saez, Jean-Luc Ferat, Michael Costanzo, Charles M. Boone, Rita S. Cha
פורמט: Artigo
שפה:Inglês
יצא לאור: Shared Science Publishers OG 2019-05-01
סדרה:Microbial Cell
נושאים:
Rnr1
Rnr3
Mec1
carbon source
respiration
mitochondria
dNTP
גישה מקוונת:http://microbialcell.com/researcharticles/2019a-corcoles-saez-microbial-cell/
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