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Subcellular localization of yeast ribonucleotide reductase regulated by the DNA replication and damage checkpoint pathways

The fidelity of DNA replication and repair processes is critical for maintenance of genomic stability. Ribonucleotide reductase (RNR) catalyzes the rate-limiting step in dNTP production and thus plays an essential role in DNA synthesis. The level and activity of RNR are highly regulated by the cell...

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Hlavní autoři: Yao, Ruojin, Zhang, Zhen, An, Xiuxiang, Bucci, Brigid, Perlstein, Deborah L., Stubbe, JoAnne, Huang, Mingxia
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC164498/
https://ncbi.nlm.nih.gov/pubmed/12732713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1131932100
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