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DNA damage signaling triggers the cytoplasm-to-vacuole pathway of autophagy to regulate cell cycle progression

Budding yeast cells suffering a single unrepaired DNA double-strand break (DSB) trigger the ATR (Mec1)-dependent DNA damage checkpoint and arrest prior to anaphase for 12–15 h, following which they adapt and resume cell division. When the DNA lesion can be repaired, the checkpoint is extinguished an...

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Bibliografische gegevens
Hoofdauteurs: Eapen, Vinay V., Haber, James E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590272/
https://ncbi.nlm.nih.gov/pubmed/23322149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.23280
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