A pathway of targeted autophagy is induced by DNA damage in budding yeast

Autophagy plays a central role in the DNA damage response (DDR) by controlling the levels of various DNA repair and checkpoint proteins; however, how the DDR communicates with the autophagy pathway remains unknown. Using budding yeast, we demonstrate that global genotoxic damage or even a single unr...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Eapen, Vinay V., Waterman, David P., Bernard, Amélie, Schiffmann, Nathan, Sayas, Enrich, Kamber, Roarke, Lemos, Brenda, Memisoglu, Gonen, Ang, Jessie, Mazella, Allison, Chuartzman, Silvia G., Loewith, Robbie J., Schuldiner, Maya, Denic, Vladimir, Klionsky, Daniel J., Haber, James E.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2017
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320992/
https://ncbi.nlm.nih.gov/pubmed/28154131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1614364114
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