A pathway of targeted autophagy is induced by DNA damage in budding yeast

Autophagy plays a central role in the DNA damage response (DDR) by controlling the levels of various DNA repair and checkpoint proteins; however, how the DDR communicates with the autophagy pathway remains unknown. Using budding yeast, we demonstrate that global genotoxic damage or even a single unr...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Eapen, Vinay V., Waterman, David P., Bernard, Amélie, Schiffmann, Nathan, Sayas, Enrich, Kamber, Roarke, Lemos, Brenda, Memisoglu, Gonen, Ang, Jessie, Mazella, Allison, Chuartzman, Silvia G., Loewith, Robbie J., Schuldiner, Maya, Denic, Vladimir, Klionsky, Daniel J., Haber, James E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2017
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320992/
https://ncbi.nlm.nih.gov/pubmed/28154131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1614364114
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