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DNA damage signaling triggers the cytoplasm-to-vacuole pathway of autophagy to regulate cell cycle progression
Budding yeast cells suffering a single unrepaired DNA double-strand break (DSB) trigger the ATR (Mec1)-dependent DNA damage checkpoint and arrest prior to anaphase for 12–15 h, following which they adapt and resume cell division. When the DNA lesion can be repaired, the checkpoint is extinguished an...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3590272/ https://ncbi.nlm.nih.gov/pubmed/23322149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.23280 |
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