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Engineering antigens for in situ erythrocyte binding induces T-cell deletion
Antigens derived from apoptotic cell debris can drive clonal T-cell deletion or anergy, and antigens chemically coupled ex vivo to apoptotic cell surfaces have been shown correspondingly to induce tolerance on infusion. Reasoning that a large number of erythrocytes become apoptotic (eryptotic) and a...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3538192/ https://ncbi.nlm.nih.gov/pubmed/23248266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216353110 |
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