Structurally conserved erythrocyte-binding domain in Plasmodium provides a versatile scaffold for alternate receptor engagement

Understanding how malaria parasites gain entry into human red blood cells is essential for developing strategies to stop blood stage infection. Plasmodium vivax preferentially invades reticulocytes, which are immature red blood cells. The organism has two erythrocyte-binding protein families: namely...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gruszczyk, Jakub, Lim, Nicholas T. Y., Arnott, Alicia, He, Wen-Qiang, Nguitragool, Wang, Roobsoong, Wanlapa, Mok, Yee-Foong, Murphy, James M., Smith, Katherine R., Lee, Stuart, Bahlo, Melanie, Mueller, Ivo, Barry, Alyssa E., Tham, Wai-Hong
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720341/
https://ncbi.nlm.nih.gov/pubmed/26715754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516512113
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