Structurally conserved erythrocyte-binding domain in Plasmodium provides a versatile scaffold for alternate receptor engagement

Understanding how malaria parasites gain entry into human red blood cells is essential for developing strategies to stop blood stage infection. Plasmodium vivax preferentially invades reticulocytes, which are immature red blood cells. The organism has two erythrocyte-binding protein families: namely...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Gruszczyk, Jakub, Lim, Nicholas T. Y., Arnott, Alicia, He, Wen-Qiang, Nguitragool, Wang, Roobsoong, Wanlapa, Mok, Yee-Foong, Murphy, James M., Smith, Katherine R., Lee, Stuart, Bahlo, Melanie, Mueller, Ivo, Barry, Alyssa E., Tham, Wai-Hong
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720341/
https://ncbi.nlm.nih.gov/pubmed/26715754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516512113
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