Structurally conserved erythrocyte-binding domain in Plasmodium provides a versatile scaffold for alternate receptor engagement

Understanding how malaria parasites gain entry into human red blood cells is essential for developing strategies to stop blood stage infection. Plasmodium vivax preferentially invades reticulocytes, which are immature red blood cells. The organism has two erythrocyte-binding protein families: namely...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Gruszczyk, Jakub, Lim, Nicholas T. Y., Arnott, Alicia, He, Wen-Qiang, Nguitragool, Wang, Roobsoong, Wanlapa, Mok, Yee-Foong, Murphy, James M., Smith, Katherine R., Lee, Stuart, Bahlo, Melanie, Mueller, Ivo, Barry, Alyssa E., Tham, Wai-Hong
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
Soggetti:
PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720341/
https://ncbi.nlm.nih.gov/pubmed/26715754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516512113
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