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Breaking tolerance with engineered class I antigen-presenting molecules

Successful efforts to activate T cells capable of recognizing weak cancer-associated self-antigens have employed altered peptide antigens to activate T cell responses capable of cross-reacting on native tumor-associated self. A limitation of this approach is the requirement for detailed knowledge ab...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Parks, Christopher A., Henning, Kalli R., Pavelko, Kevin D., Hansen, Michael J., Van Keulen, Virginia P., Reed, Brendan K., Stone, Jennifer D., Schrum, Adam G., Gil, Diana, Kranz, David M., Bordner, Andrew J., Barry, Michael A., Pease, Larry R.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6386718/
https://ncbi.nlm.nih.gov/pubmed/30728302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1807465116
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