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Gut dysbiosis breaks immunological tolerance toward the central nervous system during young adulthood
Multiple sclerosis (MS) is an autoimmune disease targeting the central nervous system (CNS) mainly in young adults, and a breakage of immune tolerance to CNS self-antigens has been suggested to initiate CNS autoimmunity. Age and microbial infection are well-known factors involved in the development...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5676872/ https://ncbi.nlm.nih.gov/pubmed/29078267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1615715114 |
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