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Gut dysbiosis breaks immunological tolerance toward the central nervous system during young adulthood

Multiple sclerosis (MS) is an autoimmune disease targeting the central nervous system (CNS) mainly in young adults, and a breakage of immune tolerance to CNS self-antigens has been suggested to initiate CNS autoimmunity. Age and microbial infection are well-known factors involved in the development...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Yadav, Sudhir K., Boppana, Sridhar, Ito, Naoko, Mindur, John E., Mathay, Martin T., Patel, Ankoor, Dhib-Jalbut, Suhayl, Ito, Kouichi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676872/
https://ncbi.nlm.nih.gov/pubmed/29078267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1615715114
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