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Gut dysbiosis breaks immunological tolerance toward the central nervous system during young adulthood

Multiple sclerosis (MS) is an autoimmune disease targeting the central nervous system (CNS) mainly in young adults, and a breakage of immune tolerance to CNS self-antigens has been suggested to initiate CNS autoimmunity. Age and microbial infection are well-known factors involved in the development...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Yadav, Sudhir K., Boppana, Sridhar, Ito, Naoko, Mindur, John E., Mathay, Martin T., Patel, Ankoor, Dhib-Jalbut, Suhayl, Ito, Kouichi
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676872/
https://ncbi.nlm.nih.gov/pubmed/29078267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1615715114
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