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Engineering antigens for in situ erythrocyte binding induces T-cell deletion

Antigens derived from apoptotic cell debris can drive clonal T-cell deletion or anergy, and antigens chemically coupled ex vivo to apoptotic cell surfaces have been shown correspondingly to induce tolerance on infusion. Reasoning that a large number of erythrocytes become apoptotic (eryptotic) and a...

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Detalhes bibliográficos
Main Authors: Kontos, Stephan, Kourtis, Iraklis C., Dane, Karen Y., Hubbell, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538192/
https://ncbi.nlm.nih.gov/pubmed/23248266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216353110
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