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Nanoparticle conjugation of antigen enhances cytotoxic T-cell responses in pulmonary vaccination

The ability of vaccines to induce memory cytotoxic T-cell responses in the lung is crucial in stemming and treating pulmonary diseases caused by viruses and bacteria. However, most approaches to subunit vaccines produce primarily humoral and only to a lesser extent cellular immune responses. We deve...

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Detalhes bibliográficos
Main Authors: Nembrini, Chiara, Stano, Armando, Dane, Karen Y., Ballester, Marie, van der Vlies, André J., Marsland, Benjamin J., Swartz, Melody A., Hubbell, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207697/
https://ncbi.nlm.nih.gov/pubmed/21969597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1104264108
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