Extracellular Nef Protein Targets CD4(+) T Cells for Apoptosis by Interacting with CXCR4 Surface Receptors

The effects of soluble Nef protein on CD4(+) T cells were examined. CD4(+)-T-cell cultures exposed to soluble Nef were analyzed for apoptosis by terminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling and hallmarks of apoptosis including cytoplasmic shrinkage, nuclear fragmentati...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: James, Cleve O., Huang, Ming-Bo, Khan, Mafuz, Garcia-Barrio, Minerva, Powell, Michael D., Bond, Vincent C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2004
Gaiak:
Virus-Cell Interactions
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC353732/
https://ncbi.nlm.nih.gov/pubmed/14990729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.6.3099-3109.2004
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