Small molecule CXCR4 antagonists block the HIV-1 Nef/CXCR4 axis and selectively initiate the apoptotic program in breast cancer cells

The chemokine receptor CXCR4 plays an integral role in the development of highly metastatic breast cancer and in the pathogenesis of chronic HIV infection. In this study, we compared the effects of CXCR4 antagonists on apoptosis induction in hematopoietic cells and in tumor cells. We incubated cells...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Huang, Ming-Bo, Giesler, Kyle E., Katzman, Brooke M., Prosser, Anthony R., Truax, Valarie, Liotta, Dennis C., Wilson, Lawrence J., Bond, Vincent C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2018
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908301/
https://ncbi.nlm.nih.gov/pubmed/29682200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24580
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi