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CCR5 receptor antagonists in preclinical to phase II clinical development for treatment of HIV

INTRODUCTION: The chemokine receptor CCR5 has garnered significant attention in recent years as a target to treat HIV infection largely due to the approval and success of the drug Maraviroc. The side effects and inefficiencies with other first generation agents led to failed clinical trials, prompti...

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Dettagli Bibliografici
Pubblicato in:Expert Opin Investig Drugs
Autori principali: Kim, Michelle B., Giesler, Kyle E., Tahirovic, Yesim A., Truax, Valarie M., Liotta, Dennis C., Wilson, Lawrence J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776690/
https://ncbi.nlm.nih.gov/pubmed/27791451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13543784.2016.1254615
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