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CCR5 receptor antagonists in preclinical to phase II clinical development for treatment of HIV

INTRODUCTION: The chemokine receptor CCR5 has garnered significant attention in recent years as a target to treat HIV infection largely due to the approval and success of the drug Maraviroc. The side effects and inefficiencies with other first generation agents led to failed clinical trials, prompti...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Expert Opin Investig Drugs
Prif Awduron: Kim, Michelle B., Giesler, Kyle E., Tahirovic, Yesim A., Truax, Valarie M., Liotta, Dennis C., Wilson, Lawrence J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776690/
https://ncbi.nlm.nih.gov/pubmed/27791451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13543784.2016.1254615
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