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Characterization of Nef-CXCR4 Interactions Important for Apoptosis Induction
The HIV-1 Nef protein was analyzed for apoptotic structural motifs that interact with the CXCR4 receptor and induce apoptosis in CD4(+) lymphocytes. Two apoptotic motifs were identified. One centered on Nef amino acids (aa) 50 to 60, with the overlapping 20-mer peptides retaining about 82% of the ac...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC521796/ https://ncbi.nlm.nih.gov/pubmed/15452229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.20.11084-11096.2004 |
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