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Extracellular Nef Protein Targets CD4(+) T Cells for Apoptosis by Interacting with CXCR4 Surface Receptors
The effects of soluble Nef protein on CD4(+) T cells were examined. CD4(+)-T-cell cultures exposed to soluble Nef were analyzed for apoptosis by terminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling and hallmarks of apoptosis including cytoplasmic shrinkage, nuclear fragmentati...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2004
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC353732/ https://ncbi.nlm.nih.gov/pubmed/14990729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.6.3099-3109.2004 |
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