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Directed Evolution of a Model Primordial Enzyme Provides Insights into the Development of the Genetic Code

The contemporary proteinogenic repertoire contains 20 amino acids with diverse functional groups and side chain geometries. Primordial proteins, in contrast, were presumably constructed from a subset of these building blocks. Subsequent expansion of the proteinogenic alphabet would have enhanced the...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Müller, Manuel M., Allison, Jane R., Hongdilokkul, Narupat, Gaillon, Laurent, Kast, Peter, van Gunsteren, Wilfred F., Marlière, Philippe, Hilvert, Donald
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536711/
https://ncbi.nlm.nih.gov/pubmed/23300488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003187
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