Low-Level Persistence of Drug Resistance Mutations in Hepatitis B Virus-Infected Subjects with a Past History of Lamivudine Treatment

We sought to determine the prevalence of hepatitis B virus (HBV) lamivudine (LAM)-resistant minority variants in subjects who once received LAM but had discontinued it prior to virus sampling. We performed direct PCR Sanger sequencing and ultradeep pyrosequencing (UDPS) of HBV reverse transcriptase...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Margeridon-Thermet, Severine, Svarovskaia, Evguenia S., Babrzadeh, Farbod, Martin, Ross, Liu, Tommy F., Pacold, Mary, Reuman, Elizabeth C., Holmes, Susan P., Borroto-Esoda, Katyna, Shafer, Robert W.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2013
נושאים:
Antiviral Agents
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535911/
https://ncbi.nlm.nih.gov/pubmed/23114756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01601-12
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