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Loss of integrin α3 prevents skin tumor formation by promoting epidermal turnover and depletion of slow-cycling cells
Progression through the various stages of skin tumorigenesis is correlated with an altered expression of the integrin α3β1, suggesting that it plays an important role in the tumorigenic process. Using epidermis-specific Itga3 KO mice subjected to the 7,12-dimethylbenzanthracene (DMBA)/12-O-tetradeca...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3535625/ https://ncbi.nlm.nih.gov/pubmed/23236172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204614110 |
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