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Loss of integrin α3 prevents skin tumor formation by promoting epidermal turnover and depletion of slow-cycling cells
Progression through the various stages of skin tumorigenesis is correlated with an altered expression of the integrin α3β1, suggesting that it plays an important role in the tumorigenic process. Using epidermis-specific Itga3 KO mice subjected to the 7,12-dimethylbenzanthracene (DMBA)/12-O-tetradeca...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3535625/ https://ncbi.nlm.nih.gov/pubmed/23236172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204614110 |
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