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EGF-induced MAPK Signaling Inhibits Hemidesmosome Formation through Phosphorylation of the Integrin β4

Migration of keratinocytes requires a regulated and dynamic turnover of hemidesmosomes (HDs). We and others have previously identified three serine residues on the integrin β4 cytoplasmic domain that play a critical role in the regulation of HD disassembly. In this study we show that only two of the...

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Détails bibliographiques
Auteurs principaux: Frijns, Evelyne, Sachs, Norman, Kreft, Maaike, Wilhelmsen, Kevin, Sonnenberg, Arnoud
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988370/
https://ncbi.nlm.nih.gov/pubmed/20870721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.138818
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