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Serine Phosphorylation of the Integrin β4 Subunit Is Necessary for Epidermal Growth Factor Receptor–induced Hemidesmosome Disruption

Hemidesmosomes (HDs) are multiprotein adhesion complexes that promote attachment of epithelial cells to the basement membrane. The binding of α6β4 to plectin plays a central role in their assembly. We have defined three regions on β4 that together harbor all the serine and threonine phosphorylation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wilhelmsen, Kevin, Litjens, Sandy H.M., Kuikman, Ingrid, Margadant, Coert, van Rheenen, Jacco, Sonnenberg, Arnoud
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951768/
https://ncbi.nlm.nih.gov/pubmed/17615294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-04-0306
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