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Dual Role of α6β4 Integrin in Epidermal Tumor Growth: Tumor-suppressive Versus Tumor-promoting Function

An increased expression of the integrin α6β4 is correlated with a poor prognosis in patients with squamous cell carcinomas. However, little is known about the role of α6β4 in the early stages of tumor development. We have isolated cells from mouse skin (mouse tumor-initiating cells [mTICs]) that are...

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Detalhes bibliográficos
Main Authors: Raymond, Karine, Kreft, Maaike, Song, Ji-Ying, Janssen, Hans, Sonnenberg, Arnoud
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043572/
https://ncbi.nlm.nih.gov/pubmed/17699601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-08-0720
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