Integrin α3β1 in hair bulge stem cells modulates CCN2 expression and promotes skin tumorigenesis

Epidermal-specific deletion of integrin α3β1 almost completely prevents the formation of papillomas during 7,12-Dimethylbenz[a]anthracene/12-O-tetradecanoylphorbol-13-acetate (DMBA/TPA) two-stage skin carcinogenesis. This dramatic decrease in tumorigenesis was thought to be due to an egress and prem...

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Detalhes bibliográficos
Publicado no:Life Sci Alliance
Main Authors: Ramovs, Veronika, Krotenberg Garcia, Ana, Song, Ji-Ying, de Rink, Iris, Kreft, Maaike, Goldschmeding, Roel, Sonnenberg, Arnoud
Formato: Artigo
Idioma:Inglês
Publicado em: Life Science Alliance LLC 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240742/
https://ncbi.nlm.nih.gov/pubmed/32423907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000645
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