Dynamics of the Translocation Step Measured in Individual DNA Polymerase Complexes

Complexes formed between the bacteriophage phi29 DNA polymerase (DNAP) and DNA fluctuate between the pre-translocation and post-translocation states on the millisecond time scale. These fluctuations can be directly observed with single-nucleotide precision in real-time ionic current traces when indi...

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Hlavní autoři: Lieberman, Kate R., Dahl, Joseph M., Mai, Ai H., Akeson, Mark, Wang, Hongyun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535181/
https://ncbi.nlm.nih.gov/pubmed/23101437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3090302
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