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Specific Nucleotide Binding and Rebinding to Individual DNA Polymerase Complexes Captured on a Nanopore
Nanoscale pores are a tool for single molecule analysis of DNA or RNA processing enzymes. Monitoring catalytic activity in real time using this technique requires that these enzymes retain function while held atop a nanopore in an applied electric field. Using an α-hemolysin nanopore, we measured th...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2666922/ https://ncbi.nlm.nih.gov/pubmed/19275265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja809663f |
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