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Measuring and modeling the kinetics of individual DNA-DNA polymerase complexes on a nanopore

The assembly of a DNA-DNA polymerase binary complex is the precursory step in genome replication, in which the enzyme binds to the 3 prime junction created when a primer binds to it’s complementary substrate. In this study, we use an active control method for observing the binding interaction betwee...

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Bibliografske podrobnosti
Main Authors: Wang, Hongyun, Hurt, Nicholas, Dunbar, William B.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682681/
https://ncbi.nlm.nih.gov/pubmed/23565679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn401180j
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