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Kinetic Mechanism at the Branchpoint between the DNA Synthesis and Editing Pathways in Individual DNA Polymerase Complexes

[Image: see text] Exonucleolytic editing of incorrectly incorporated nucleotides by replicative DNA polymerases (DNAPs) plays an essential role in the fidelity of DNA replication. Editing requires that the primer strand of the DNA substrate be transferred between the DNAP polymerase and exonuclease...

詳細記述

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書誌詳細
主要な著者: Lieberman, Kate R., Dahl, Joseph M., Wang, Hongyun
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2014
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046759/
https://ncbi.nlm.nih.gov/pubmed/24761828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja5026408
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