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Direct Observation of Translocation in Individual DNA Polymerase Complexes
Complexes of phi29 DNA polymerase and DNA fluctuate on the millisecond time scale between two ionic current amplitude states when captured atop the α-hemolysin nanopore in an applied field. The lower amplitude state is stabilized by complementary dNTP and thus corresponds to complexes in the post-tr...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3339981/ https://ncbi.nlm.nih.gov/pubmed/22378784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.338418 |
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