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Modulation of DNA Polymerase Noncovalent Kinetic Transitions by Divalent Cations
Replicative DNA polymerases (DNAPs) require divalent metal cations for phosphodiester bond formation in the polymerase site and for hydrolytic editing in the exonuclease site. Me(2+) ions are intimate architectural components of each active site, where they are coordinated by a conserved set of amin...
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| 出版年: | J Biol Chem |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4813572/ https://ncbi.nlm.nih.gov/pubmed/26797125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.701797 |
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