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Different Divalent Cations Alter the Kinetics and Fidelity of DNA Polymerases
Divalent metal ions are essential components of DNA polymerases both for catalysis of the nucleotidyl transfer reaction and for base excision. They occupy two sites, A and B, for DNA synthesis. Recently, a third metal ion was shown to be essential for phosphoryl transfer reaction. The metal ion in t...
Guardat en:
| Publicat a: | J Biol Chem |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5076500/ https://ncbi.nlm.nih.gov/pubmed/27462081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R116.742494 |
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