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The kinetic and chemical mechanism of high-fidelity DNA polymerases

This review summarizes our current understanding of the structural, kinetic and thermodynamic basis for the extraordinary accuracy of high fidelity DNA polymerases. High fidelity DNA polymerases, such as the enzyme responsible for the replication of bacteriophage T7 DNA, discriminate against similar...

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Bibliografski detalji
Glavni autor: Johnson, Kenneth A.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047511/
https://ncbi.nlm.nih.gov/pubmed/20079883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2010.01.006
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