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The kinetic and chemical mechanism of high-fidelity DNA polymerases
This review summarizes our current understanding of the structural, kinetic and thermodynamic basis for the extraordinary accuracy of high fidelity DNA polymerases. High fidelity DNA polymerases, such as the enzyme responsible for the replication of bacteriophage T7 DNA, discriminate against similar...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3047511/ https://ncbi.nlm.nih.gov/pubmed/20079883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2010.01.006 |
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