Kinetic Approaches to Understanding the Mechanisms of Fidelity of the Herpes Simplex Virus Type 1 DNA Polymerase

We discuss how the results of presteady-state and steady-state kinetic analysis of the polymerizing and excision activities of herpes simplex virus type 1 (HSV-1) DNA polymerase have led to a better understanding of the mechanisms controlling fidelity of this important model replication polymerase....

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Bibliographic Details
Main Authors: Zhu, Yali, Stroud, Jason, Song, Liping, Parris, Deborah S.
Format: Artigo
Language:Inglês
Published: SAGE-Hindawi Access to Research 2010
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010682/
https://ncbi.nlm.nih.gov/pubmed/21197400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/631595
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