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Mechanisms by which Herpes Simplex Virus DNA Polymerase Limits Translesion Synthesis through Abasic Sites

Results suggest a high probability that abasic (AP) sites occur at least once per herpes simplex virus type 1 (HSV-1) genome. The parameters that control the ability of HSV-1 DNA polymerase (pol) to engage in AP translesion synthesis (TLS) were examined because AP lesions could influence the complet...

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Detalhes bibliográficos
Main Authors: Zhu, Yali, Song, Liping, Stroud, Jason, Parris, Deborah S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777399/
https://ncbi.nlm.nih.gov/pubmed/17904428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2007.08.001
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